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. Author manuscript; available in PMC: 2015 May 30.
Published in final edited form as: Adv Immunol. 2014;124:1–16. doi: 10.1016/B978-0-12-800147-9.00001-7

Figure 2.

Figure 2

Lung ILC2s mediate eosinophilic airway inflammation and pathology in mice exposed to fungal allergen Alternaria. (A) ILC2s were isolated from the lungs of naïve C57BL/6 mice, and they were adoptively transferred to naive Il7r−/− mice, which are deficient in mature CD4+ T cells and ILCs. Mice were then exposed intranasally three times to PBS or Alternaria extract over 6 days. Cell number and differentials in BAL fluids were determined. (B) Representative histology (upper panels: H&E staining, lower panels: PAS staining) of the mice as described in A.