Fig 6.
L-glutamine (Gln) and pyrrophenone suppress bronchoalveolar lavage (BAL) levels of leukotriene B4 (LTB4) and platelet activating factor (PAF). BAL fluid levels of LTB4 (a) and PAF (b) were determined at the indicated time-points. Gln [750 mg/kg, intraperitoneally (i.p.)] and pyrrophenone (Pyr; 20 mg/kg, i.p.) were administered immediately after and 30 min before the second airway challenge, respectively. (c) LTB4 and PAF were measured at 3 h. Data representing the mean ± standard deviation (s.d.) of three independent experiments with three to five mice/group/experiment are shown. *P < 0·05 compared to saline control; **P < 0·01 compared to saline control; #P < 0·05 compared to ovalbumin (OVA) challenge group.