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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Mod Pathol. 2015 Feb 13;28(6):845–853. doi: 10.1038/modpathol.2015.6

Figure 3.

Figure 3

Pathway analysis reveals down regulation of Pol II Elongation genes in TCEB1 mutated tumors. A) Heatmap of mRNA expression of Pol II elongation genes stratified by TCEB1 mutation and concomitant loss of heterozygosity (loss of heterozygosity ), loss of heterozygosity alone, and in the wildtype setting. B) Box plot of specific Pol II elongation genes demonstrating a lack of expression changes in tumors with loss of heterozygosity alone compared to combined TCEB1 mutation and loss of heterozygosity .