Table 4.

Concentrations (ng/mL) of 13 organochlorine compounds in the extracts of 12 samples of North Sea harbour porpoise blubber, in culture medium solution to which the ER sensitive cells were exposed in the cell based assay (calculated from GC-MS data from Table 3; according to that 1 mL of culture medium contains the contaminants extracted from 0.04 g of fat). For the samples displaying an estrogenic activity, the percentage of relative response compared to the maximal response induced by E2 is indicated between brackets.

	03/1521	01/1196	03/1238	A00/1140	A00/258	A03/1517	01/847	01/805	01/1219	A00/600	01/887	A00/974
PCB 138	4.0 × 101	5.2 × 101	3.3 × 102	1.5 × 101	1.5 × 102	1.3 × 103	1.1 × 102	1.5 × 102	3.1 × 102	1.4 × 102	9.1 × 101	2.4 × 101
PCB 153	5.4 × 101	6.7 × 101	4.9 × 102	2.5 × 102	2.2 × 102	1.7 × 103	1.6 × 102	2.2 × 102	4.5 × 102	2.1 × 102	1.3 × 102	2.4 × 101
PCB 180	1.3 × 101	1.3 × 101	1.0 × 102	7.3 × 101	4.7 × 101	3.0 × 102	3.2 × 101	4.9 × 101	7.5 × 101	3.7 × 101	3.1 × 101	4.5 × 100
Σ (3) PCBs	1.1 × 102	1.3 × 102	9.2 × 102	4.8 × 102	4.2 × 102	3.2 × 103	3.0 × 102	4.2 × 102	8.4 × 102	3.9 × 102	2.5 × 102	5.2 × 101
o,p′-DDT	1.9 × 100	4.2 × 100	1.4 × 101	3.9 × 100	3.0 × 100	8.5 × 100	2.4 × 100	3.3 × 100	3.4 × 101	2.2 × 100	6.7 × 100	2.8 × 100
o,p′-DDD	n/a	2.9 × 100	7.2 × 100	3.1 × 100	2.7 × 100	1.7 × 101	n/a	3.4 × 100	2.1 × 101	n/a	2.8 × 100	1.6 × 100
p,p′-DDT	7.2 × 100	1.3 × 101	3.2 × 101	2.2 × 101	1.9 × 101	2.8 × 101	7.5 × 100	1.5 × 101	5.6 × 101	8.0 × 100	2.3 × 101	4.3 × 100
p,p′-DDD	1.4 × 101	2.1 × 101	3.5 × 101	3.7 × 101	3.4 × 101	5.0 × 101	9.5 × 100	2.9 × 101	1.0 × 102	1.6 × 101	2.4 × 101	5.6 × 100
p,p′-DDE	4.2 × 101	5.0 × 101	1.2 × 102	1.1 × 102	1.2 × 102	1.6 × 102	3.6 × 101	9.6 × 101	3.4 × 102	5.6 × 101	9.3 × 101	2.0 × 101
Σ (5) DDTs	6.4 × 101	9.1 × 101	2.1 × 102	1.7 × 102	1.8 × 102	2.7 × 102	5.6 × 101	1.5 × 102	5.6 × 102	8.2 × 101	1.5 × 102	3.5 × 101
β-HCH	n/a	n/a	3.9 × 100	n/a	3.5 × 100	3.2 × 100	n/a	3.3 × 100	5.0 × 100	1.7 × 100	3.0 × 100	1.9 × 100
δ-HCH	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
γ-HCH	3.9 × 100	5.8 × 100	5.3 × 100	5.1 × 100	9.4 × 100	7.8 × 100	3.2 × 100	6.9 × 100	1.9 × 101	7.0 × 100	6.1 × 100	4.6 × 100
α-HCH	2.8 × 100	n/a	2.7 × 100	2.6 × 100	n/a	n/a	n/a	3.2 × 100	3.9 × 100	2.8 × 100	4.2 × 100	3.0 × 100
HCB	5.7 × 100	8.4 × 100	2.1 × 101	8.9 × 100	1.2 × 101	2.0 × 101	5.4 × 100	1.3 × 101	6.1 × 101	3.9 × 100	2.4 × 101	3.0 × 100
Σ (5) HCHs + HCB	1.2 × 101	1.4 × 101	3.3 × 101	1.7 × 101	2.5 × 101	3.1 × 101	8.6 × 100	2.7 × 101	8.9 × 101	1.5 × 101	3.7 × 101	1.3 × 101
Σ (13) total	1.9 × 102	2.4 × 102	1.2 × 103	6.7 × 102	6.2 × 102	3.5 × 103	3.7 × 102	5.9 × 102	1.5 × 103	4.8 × 102	4.4 × 102	9.9 × 101
Activity recorded in the ER reporter gene assay (% of relative response)	None	Antiestrogenic (7%)	Antiestrogenic (16%)	Antiestrogenic (6%)	Estrogenic (22%)	Antiestrogenic (13%)	Antiestrogenic (5%)	None	Estrogenic (24%) and antiestrogenic (6%)	Antiestrogenic (5%)	None	Antiestrogenic (7%)

n/a: not applicable.