Table 3.
In vitro clot lysis activity of Ocimum tenuiflorum, Andrographis paniculata, Adhatoda vasica, Leea macrophylla, and Litsea glutinosa.
| Herbs/drugs | Fractions | % of clot lysis (mean ± SD) |
P value (two-tailed) when compared to negative control (water) |
|---|---|---|---|
| Negative control (water) | Methanol | 8.89 ± 2.22 | — |
| Positive control (streptokinase) | Methanol | 71.14 ± 6.91 | P < 0.001 |
| Ocimum tenuiflorum | Methanol | 26.08 ± 5.12 | P < 0.001 |
| Andrographis paniculata | Methanol | 35.74 ± 6.76 | P < 0.001 |
| Adhatoda vasica | Methanol | 22.86 ± 3.61 | P < 0.001 |
| Leea macrophylla | Methanol | 47.47 ± 6.65 | P < 0.05 |
| Litsea glutinosa | Methanol | 27.25 ± 3.97 | P < 0.001 |
Values are mean ± SD (n = 20); * P < 0.05, ** P < 0.001, Dunnett test as compared to control (positive and negative). Statistical representation of the effective clot lysis percentage by herbal preparations, positive thrombolytic control (streptokinase), and negative control (sterile distilled water) processed by paired t-test analysis (Dunnett test).