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. 2015 Feb 6;11(2):e1004932. doi: 10.1371/journal.pgen.1004932

Figure 4. SF3a1 inhibition affects pre-mRNA splicing of many genes in the TLR signaling pathway.

Figure 4

The schematic depicts the Toll-like receptor signaling pathway (KEGG map04620) [143,144] with genes whose splicing is altered (DEXSeq analysis) when SF3a1 is inhibited color coded as follows: red (altered in the absence or presence of LPS), green (only in the absence of LPS), blue (only in the presence of LPS). Additionally, altered splicing of two genes in purple was identified in our other analyses. Generated using DAVID [53,54].