Fig 2. IFNγ signaling in CD11c⁺ DCs, but not myeloid cells, is required for the development of Th1-Treg cells.

FACS analysis and frequencies of T-bet⁺ or CXCR3⁺ cells in Foxp3⁺CD4⁺ Treg cells in (A) Spl and (B) LP isolated from CD11c ^cre IFNγR2 ^fl/fl, Lyz ^cre IFNγR2 ^fl/fl and WT control mice. FACS data are representative of four independent experiments (*p<0.05; **p<0.01).