Fig 7. Inhibition of CD44 blocks the development of atrophic gastritis in H. pylori infected Mongolian gerbils.

Mongolian gerbils were administered (A) Brucella broth (control), (B) H. pylori strain 7.13 alone, and in combination with either a (C) control peptide (cPep1), or (D) peptide targeting CD44 (Pep1). Gerbils were sacrificed after 6 weeks infection and H&E’s were scored using the updated Sydney classification for (E) neutrophil infiltration, (F) lymphocyte infiltration, (G) lymphoid follicles, and (H) atrophy.