Table 2.
Patient-level estimates of sensitivity and specificity for the detection of bowel inflammation (n = 24 with inflammation, n = 38 without)
| Configuration | Reader | Sensitivitya
|
Specificitya
|
||
|---|---|---|---|---|---|
| Estimate (%) | 95% CI | Estimate (%) | 95% CI | ||
| Commercial IR (ASIR/SAFIRE) | 1 | 88 | (69, 96) | 87 | (73, 94) |
| 2 | 79 | (60, 91) | 84 | (70, 93) | |
| 3 | 79 | (60, 91) | 89 | (76, 96) | |
| Pooledb | 82 | (69, 95) | 87 | (80, 94) | |
| ANLM | 1 | 83 | (64, 93) | 76 | (61, 87) |
| 2 | 88 | (69, 96) | 87 | (73, 94) | |
| 3 | 75 | (55, 88) | 89 | (76, 96) | |
| Pooledb | 82 | (70, 93) | 84 | (77, 91) | |
| FBP | 1 | 92 | (74, 98) | 87 | (73, 94) |
| 2 | 88 | (69, 96) | 84 | (70, 93) | |
| 3 | 75 | (55, 88) | 87 | (73, 94) | |
| Pooledb | 85 | (73, 97) | 86 | (78, 94) | |
a
Sensitivity and specificity are based on 24 patients with at least one inflamed segment and 38 patients without, respectively
b
Pooled estimates of sensitivity and specificity have been adjusted for the correlation of readers within case through generalized estimating equations