Table 3.

Time and Events Schedule

Visit	V0	V1 Part 1a	V1 Part 2b	V2	V3	V4	V5	V6 Part 1a	V6 Part 2b
Time Window (weeks)		−12 to −10	−10 to −6	−6 to −2		2–4	5–7	11–13
Target (week)		−11	−8	−4	0	3	6	12
Type of visit 1	Pre V1 Eligibility	Phone	Clinic	iPad/ FaceTime	iPad FaceTime	iPad FaceTime	iPad FaceTime	iPad FaceTime	Clinic
Trial Randomization	x
Consent		x
Eligibility evaluation2	x	x	x		x
Procedures
Pregnancy test			x
Blood (DNA, allergy)									x
Height and Weight3			x	x	x		x	x	x
Vital Signs			x						x
Physical Exam			x						x
Treatment Randomization5					x
Consent Interview		x						x
Exhaled nitric oxide (selected sites)			x						x
Spirometry Pre and Post 6			x	x	x	x	x
Questionnairesc
Screening Form		x			x
Baseline asthma and medical history			x
Asthma Control Test			x	x	x	x	x	x
Children’s Health Survey for Asthma			x		x		x	x
Clinic Visit Form				x	x	x	x	x
EQ-5D			x					x
Quality of Life			x		x		x	x
Complete Morning and Evening reports on iPad				x	x	x	x	x
Medication and device distribution
Treatment medication distribution4	x	x	x	x	x	x	x
iPad Daily Report/PEF/AAP review	x	x	x	x	x	x
Receive/Return iPad and EasyOne8	x						X

^aConducted during FaceTime visit

^bConducted at clinic site

^cQuestionnaires are completed online prior to each iPad/FaceTime visit