Table 1.
Baseline characteristics of Brazilian and Portuguese study population according to non-alcoholic fatty liver disease status n (%)
|
Brazil (n = 131) |
Portugal (n = 90) |
|||||
| NASH | S. Steatosis | P-value | NASH | S. Steatosis | P-value | |
| 86 (65.6) | 45 (34.4) | 24 (26.7) | 66 (73.3) | |||
| Gender | ||||||
| Female | 61 (70.1) | 26 (29.9) | 0.2 | 20 (28.6) | 50 (71.4) | 0.6 |
| Male | 25 (56.8) | 19 (43.2) | 4 (20.0) | 16 (80.0) | ||
| Age (yr) | 56 ± 1.1 | 51 ± 1.5 | 20.006 | 47 ± 12.4 | 47 ± 10.2 | 0.3 |
| Diabetes-2 | 71 (82.4) | 8 (17.6) | 23.7 × 10-9 | 14 (33.3) | 28 (66.7) | 0.2 |
| Fasting glucose (mg/dL) | 124.9 ± 5.2 | 106.0 ± 5.3 | 20.001 | 97.3 ± 28.2 | 92.6 ± 18.4 | 0.3 |
| HOMA ≥ 2.5 - mean | 5.3 | 4.6 | 20.04 | 4.9 | 4.8 | 0.5 |
| HOMA ≥ 2.5 - n | 75 (70.8) | 31 (29.2) | 20.02 | 15 (45.5) | 18 (54.5) | 0.5 |
| Hypertension | 59 (68.2) | 14 (31.8) | 28.0 × 10-5 | 12 (20.1) | 34 (73.9) | 20.003 |
| ALT (IU/L) | 38.3 ± 0.6 | 33 ± 5.2 | 0.2 | 31.7 ± 30.6 | 30.56 ± 15.9 | 0.7 |
| AST (IU/L) | 22 ± 22.5 | 32.8 ± 3.2 | 20.009 | 25.9 ± 24.8 | 25.06 ± 11.2 | 0.7 |
| 1Dyslipidemia | 54 (63.0) | 17 (37.0) | 20.009 | 24 (100) | 55 (83) | 20.03 |
1
High levels of cholesterol and/or triglyceride;
2
Statistically significant results, P < 0.05. NASH: Nonalcoholic steatohepatitis; S. Steatosis: Simple steatosis; HOMA: Homeostatic Model of Assessment; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.