Skip to main content
. 2015 May 18;2015:738241. doi: 10.1155/2015/738241

Figure 5.

Figure 5

p38 involved in heteronemin-induced cell apoptosis in A498 cells. (a) p38 inhibitor, SB203580, was preincubated for 30 min and cell viability was determined by MTT assay. ∗∗∗ P < 0.001 compared with the control group. # P < 0.05 and ### P < 0.001 compared with the heteronemin-treated group. p38 siRNA was transfected to evaluate the role in heteronemin-induced A498 cell death by using the MTT assay (b), expression of apoptosis-related proteins (PARP and procaspase-3) (c) for 24 h. H and SB are indicated as heteronemin 3 μM and SB203580 25 μM, respectively. CTL is indicated as control.