Figure 1.

Loss and recovery of contractile torque after large-strain injury. The data indicate that dysferlin-deficient muscle is not more susceptible to initial injury compared with dysferlin-sufficient muscle. Partial recovery occurs over 3 to 6 hours in both dysferlin-sufficient A/WySnJ and dysferlin-deficient A/J muscle, after which A/J muscle (gray bars) loses contractile torque whereas A/WySnJ muscle (white bars) continues to recover. ^∗P < 0.05 versus approximately 10 minutes; ^†P < 0.05 versus 3 hours; ^‡P < 0.05 versus preceding time point other than approximately 10 minutes or 3 hours; and ^§P < 0.05 between strains.