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Structure of KSHV LANA bound to LBS1 DNA. (A) Crystal structure of an oligomerization-deficient LANA(1008–1146) multiple-point mutant bound to 20-bp LBS1 DNA. (B) Close-up of the primary site of DNA recognition. (C) Close-up of the symmetry-related secondary site. (D) Structure-derived interaction chart. LBS1 sequence numbering corresponds to a previous study (17).
