Table 3.
Changes (%) in mean and maximum BOLD activities in 3 Brodmann areas (BA) during the motor task at session 1 (baseline), 2 (6 weeks), and 3 (12 weeks)
| BA4a | ||||||
| BOLD mean | BOLD max | |||||
| Pt # | L1/L2/L3 | R1/R2/R3 | (L-R)/R % | L1/L2/L3 | R1/R2/R3 | (L-R)/R % |
| 1 | 2.90/2.02/1.86 | 3.19/0.96/0.95 | −9/11/10 | 19.5/10.1/18.9 | 22.1/5.52/13.7 | −12/84/37 |
| 2 | 2.31/3.52/3.68 | 2.86/5.58/3.80 | −19/-36/-3 | 10.9/28.4/31.7 | 16.5/33.5/17.2 | −34/-15/85 |
| 3 | 2.24/1.43/3.3 | 2.67/1.36/2.91 | −16/5/13 | 17.8/10.9/19.7 | 19.1/8.20/15.0 | −7/33/31 |
| 4 | 1.20/2.71/2.18 | 1.59/2.50/1.82 | −25/8/20 | 8.79/26.8/15.4 | 13.8/14.9/11.9 | −36/80/30 |
| 5 | 2.76/2.64/2.58 | 1.96/3.38/2.38 | 41/11/8 | 22.4/19.8/17.0 | 18.5/13.7/9.64 | 21/45/76 |
| 6 | 3.62/0.92/0.71 | 4.69/1.05/1.28 | −23/-12/-45 | 33.1/3.52/4.35 | 32.0/7.04/15.1 | 4/-50/-71 |
| Mean | 2.51/2.21/2.39 | 2.83/2.29/2.19 | −8/14/15 | 18.8/16.6/17.8 | 20.3/13.8/13.8 | −11/29/31 |
| Healthy subjects; mean | 1.16/1.05 | 0.66/0.49* | 79/130 | 10.6/8.0 | 5.70/3.66 | 108/160 |
| p values | 0.011/0.014 | 0.001/0.001 | 0.002/0.004 | 0.034/ns | 0.001/0.001 | 0.003/0.001 |
| BA4p | ||||||
| BOLD mean | BOLD max | |||||
| Pt # | L1/L2/L3 | R1/R2/R3 | (L-R)/R % | L1/L2/L3 | R1/R2/R3 | (L-R)/R % |
| 1 | 2.37/1.50/1.55 | 2.42/0.76/0.83 | −2/98/87 | 19.5/10.1/18.9 | 22.1/4.53/13.7 | −12/123/37 |
| 2 | 1.14/2.75/2.50 | 1.88/3.44/2.77 | −39/-20/-10 | 8.11/28.4/31.7 | 12.1/22.8/17.2 | −33/25/85 |
| 3 | 1.40/0.98/2.65 | 1.16/0.73/1.44 | 21/34/84 | 10.7/7.89/18.1 | 14.0/5.18/10.8 | −24/52/67 |
| 4 | 0.99/1.41/1.26 | 1.39/1.31/1.30 | −29/8/-3 | 8.79/16.2/6.91 | 13.8/14.0/11.9 | −36/16/-42 |
| 5 | 2.27/2.12/1.45 | 1.59/1.70/2.18 | 43/24/-33 | 18.5/13.9/8.91 | 18.5/1.1/9.22 | 0/15/-3 |
| 6 | 2.96/0.86/0.61 | 2.96/0.70/0.67 | 0/22/-9 | 33.1/2.96/4.35 | 25.6/7.04/5.38 | 29/-58/-19 |
| Mean | 1.86/1.60/1.67 | 1.90/1.44/1.53 | −1/28/19 | 16.4/13.3/14.8 | 17.7/10.9/11.4 | −13/29/21 |
| Healthy subjects; mean | 0.94/0.87 | 0.51/0.37* | 85/57 | 8.08/6.73 | 4.16/2.86 | 122/149 |
| p values | 0.045/0.020 | 0.001/0.001 | 0.003/0.004 | 0.045/ns | 0.001/0.001 | 0.002/0.008 |
| BA6 | ||||||
| BOLD mean | BOLD max | |||||
| Pt # | L1/L2/L3 | R1/R2/R3 | (L-R)/R % | L1/L2/L3 | R1/R2/R3 | (L-R)/R % |
| 1 | 2.81/1.96/1.71 | 3.10/0.94/0.67 | −9/108/155 | 36.4/13.0/18.7 | 34.7/13.0/3.56 | 5/0/430 |
| 2 | 2.59/3.93/3.89 | 2.64/6.15/4.11 | −1/-36/-5 | 10.9/32.8/33.2 | 16.5/39.5/28.3 | −34/-17/17 |
| 3 | 3.08/1.78/3.81 | 2.71/1.50/3.59 | 14/0/619 | 18.3/13.8/22.7 | 19.1/9.60/20.4 | −4/44/11 |
| 4 | 1.51/1.26/2.62 | 1.30/2.28/1.98 | 16/-40/33 | 15.6/26.8/16.7 | 8.50/13.6/11.9 | 84/96/41 |
| 5 | 2.52/3.09/4.72 | 1.53/2.25/3.64 | 65/37/30 | 31.9/24.1/39.0 | 17.7/14.8/25.1 | 80/63/55 |
| 6 | 5.09/1.23/0.88 | 4.10/1.06/1.16 | 24/15/-24 | 27.0/13.9/5.99 | 32.0/10.3/15.1 | −16/35/-60 |
| Mean | 2.93/2.21/2.94 | 2.56/2.37/2.52 | 18/16/32 | 23.3/20.7/22.7 | 21.4/16.8/17.4 | 19/37/82 |
| Healthy subjects; mean | 1.09/0.94 | 0.69/0.56 | 61/76 | 12.7/9.62 | 6.08/4.69 | 119/116 |
| p values | 0.003/0.004 | 0.001/0.001 | 0.015/0.034 | 0.034/0.011 | 0.003/0.001 | 0.020/0.015 |
Values from the 10 healthy subjects studied twice serve as reference; p values refer to between-group differences. *p < 0.05 for session 1 vs. 2 in healthy subjects (p < 0.002 applying Bonferroni correction in bold font).