Table 1.

Characteristics of primary studies ( N  = 859) across and within the included meta-analyses ( N  = 46)

Number of sample size	Median	Interquartile range	Min-max
Across all meta-analyses
Number of diseased	33	17-63	0-1,358
Number of non-diseased	36	18-100	0-49,973
Sample size	87	45-185	3-50,008
Time since first publication (years)	6	3-10	0-42
	Median of the median	Interquartile range of medians	Min-max of the median
Within meta-analyses
Number of diseased	31	18-41	5-154
Number of non-diseased	38	18-87	0-11,276
Sample size	94	46-332	20-11,281
Time since first publication (years)	5	4-11	0-26