Table 2.
Children with asthma (n = 23) | Adolescents with asthma (n = 27) | Adults with asthma (n = 50) | Adults with COPD (n = 50) | Healthy adults (n = 50) | |
---|---|---|---|---|---|
Spiromax | |||||
PIF, L/min | 69.5‡ | 67.9‡ | 74.4‡ | 57.5‡ | 85.0‡ |
(17.2) | (15.1) | (18.1) | (21.0) | (13.6) | |
Max ΔP, kPa | 5.0† | 4.7* | 5.7* | 3.7† | 7.3 |
(2.4) | (2.2) | (2.6) | (2.7) | (2.3) | |
ACC, kPa/s | 13.6 | 12.1 | 15.6 | 11.0* | 15.9* |
(11.8) | (8.8) | (15.7) | (12.8) | (13.5) | |
Inhalation volume, L | 1.50† | 2.03† | 2.39† | 1.82† | 2.98* |
(0.6) | (0.81) | (1.03) | (0.88) | (1.02) | |
Turbuhaler | |||||
PIF, L/min | 58.5 | 57.8 | 65.4 | 50.1 | 78.0 |
(14.7) | (13.4) | (17.5) | (16.2) | (11.8) | |
Max ΔP, kPa | 3.9 | 3.9 | 5.1 | 3.1 | 7.0 |
(2.0) | (1.8) | (2.6) | (2.0) | (2.1) | |
ACC, kPa/s | 10.2 | 11.4 | 13.0 | 8.4 | 12.8 |
(7.7) | (7.2) | (12.1) | (9.5) | (9.6) | |
Inhalation volume, L | 1.25 | 1.68 | 2.13 | 1.58 | 2.80 |
(0.57) | (0.74) | (1.01) | (0.69) | (0.92) |
Data shown are mean (standard deviation). *p < 0.05 vs Turbuhaler; †p < 0.01 vs Turbuhaler; ‡p ≤ 0.0001 vs Turbuhaler.