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. 2015 Jun 1;5:10821. doi: 10.1038/srep10821

Figure 6. RB ameliorates olfactory memory deficits in mb;hTau flies.

Figure 6

Olfactory memory assay (larger numbers are better performance; see Olfactory memory assay in Methods). Performance index (PI) of the mb;hTau flies was significantly less than that of mb;yw flies (P = 0.0051). One-week of RB treatment significantly improved the olfactory memory of mb;hTau flies (P = 0.0158, control in light vs. RB in light). Such an improvement was not detected when flies were kept in continuous darkness during treatment (P = 0.7000, control in dark vs. RB in dark), as the performance of untreated mb;hTau flies was worsened in contrast to the flies kept under normal light cycle (P = 0.0013, control in light vs. control in dark). Statistical analyses were conducted using the Mann-Whitney test. Data are means ±SEM of control (n = 22) and RB-treated (n = 22) groups of mb;hTau flies and control (n = 11) and RB (n = 11) groups of mb;yw flies under “light” conditions and control (n = 3) and RB-treated (n = 3) groups of mb;hTau flies under “dark” conditions.