Figure 1.

T.S. of the testis of (a) a control mouse showing full spermatogenic activity in the seminiferous tubules. (b) Metronidazole (MTZ) (500 mg/kg BW/day)-treated mouse for 28 days showing shrinkage of the seminiferous tubules, depletion, disorganization, vacuolization and sloughing of the germ cells and appearance of multinucleated giant cells. (c) A mouse co-administered with MTZ (500 mg/kg BW/day) and Tribulus terrestris (TT) (100 mg/kg BW/day) for 28 days presenting partial recovery in spermatogenic activity (d) a mouse co-administered with MTZ (500 mg/kg BW/day) and TT (200 mg/kg BW/day) for 28 days showing full recovery in spermatogenic activity