Figure 2.

Primary end point: prednisone use according to initial dose and GvHD-grade at onset of symptoms. (A) Patients who presented with Grade IIa-manifestations (cohort A; n=91); initial prednisone dose, 0.5 mg/kg/day (solid line) or 1 mg/kg/day (dashed line). (B) Patients who presented with ≥grade IIb-manifestations (cohort B; n=59); initial prednisone dose, 1 mg/kg/day (solid line) or 2 mg/kg/day (dashed line). The graphs show mean prednisone doses per day until day 42 after starting treatment. Only patients who completed 42 days of prednisone treatment were included in the cumulative dose analysis (n=150).