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PSP-mediated activation of TLR4, TRAF6, NF-κB and AP-1 in B10 (TLR4+/+) and ScCr (TLR4−/−) peritoneal macrophages. Peritoneal macrophages from B10 (TLR4+/+) and ScCr (TLR4−/−) mice were cultured with PSP (25 μg/ml) or LPS (100 ng/ml) for 12 h. The levels of TLR4 (a), TRAF6 (b), P- NF-κB p65 (c) and P-c-Jun (d) were examined by Western blot. Data represent the mean ± SD of three experiments. *p < 0.05 vs. control group. ND = not detected
