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. 2015 May 26;3:e966. doi: 10.7717/peerj.966

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© 2015 Al-Brakati et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) (i) Transmission electron micrograph of rat femoral artery showing caveolae covering most of the EC membrane. IEL is the internal elastic lamina. Magnification was ×60,000. Scale bar = 1 µm. (ii) Detail from marked area in (i) showing caveolae (Cav) and caveosomes (V). (iii) After treatment with 5 mM M-β-CD, EC cell membrane was free of caveolae. (B) (i) TEM of smooth muscle cell. Magnification was ×60,000. Scale bar = 1 µm. (ii) Detail from marked area in (i) showing caveolae (Cav) and mitochondrion (M). (iii) After treatment with 5 mM M-β-CD, SMC cell membrane was free of caveolae.