TABLE 3.
aHRs of Offspring Being Diagnosed With ASD or Infantile Autism, Specifically After Self-Reported Infection During Pregnancy
| Type of Infection | ASD
|
Infantile Autism
|
|||
|---|---|---|---|---|---|
| No. Exposed ASD/Non-ASD | Crude HR (95% CI) | aHRa (95% CI) | No. Exposed Infantile Autism/Non–Infantile Autism | aHRa (95% CI) | |
| Pyelonephritis | 9/426 | 2.1 (1.1–4.0) | 1.8 (0.9–3.9) | 4/431 | NE |
| Cystitis | 123/11 244 | 1.1 (0.9–1.3) | 1.1 (0.9–1.3) | 49/11 318 | 1.2 (0.9–1.7) |
| Respiratory tract infection | 70/7322 | 0.9 (0.7–1.2) | 1.0 (0.7–1.3) | 32/7360 | 1.2 (0.8–1.8) |
| Influenza | 9/799 | 1.1 (0.6–2.1) | 1.1 (0.6–2.3) | 7/801 | 2.3 (1.0–5.3) |
| Coughb | 150/13 862 | 1.1 (0.9–1.3) | 1.0 (0.8–1.2) | 53/13 959 | 1.1 (0.8–1.5) |
| Vaginal yeast infection | 194/17 946 | 1.1 (0.9–1.3) | 1.2 (1.0–1.4) | 56/18 084 | 0.9 (0.7–1.3) |
| Treatment of yeast infectionc | 139/12 646 | 1.1 (0.9–1.3) | 1.2 (1.0–1.4) | 35/12 750 | 0.8 (0.6–1.2) |
| Venereal wartsb | 12/788 | 1.5 (0.9–2.6) | 1.6 (0.9–2.8) | 2/798 | NE |
| Genital herpesb | 14/1372 | 1.0 (0.6–1.7) | 0.7 (0.4–1.4) | 5/1381 | 0.9 (0.3–1.5) |
| Labial herpesb | 105/10 794 | 1.0 (0.8–1.2) | 1.0 (0.8–1.2) | 37/10 862 | 1.0 (0.7–1.5) |
NE, not estimated due to limited number of exposed cases (<5).
a
Adjusted for maternal age, paternal age, maternal smoking during pregnancy, parity, gender, parents’ educational status, and the parents’ psychiatric condition. Data were analyzed in strata according to year of birth.
b
Data included only information until week 32 in pregnancy.
c
Treatment includes suppository, tablets, and cream.