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. 2015 Jun 1;10(6):e0127072. doi: 10.1371/journal.pone.0127072

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© 2015 Heublein et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — Survival of TRα positive vs. negative cases (A, B) and TRβ positive vs. negative cases (C, D) was plotted in accordance with Kaplan-Meier survival curves. TRα was a negative predictor regarding five-year survival of patients carrying a BRCA1 mutation (A). In sporadic cancer cases TRα was not associated with five-year survival (B). TRβ positivity was associated with a significantly prolonged overall survival in patients carrying a BRCA1 mutation (C). In sporadic cancer cases TRβ failed to predict prognosis (D).