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. 2015 Jun 1;10(6):e0127072. doi: 10.1371/journal.pone.0127072

Table 1. Patient characteristics (whole sample).

breast cancer type BRCA1 sporadic breast cancer
BRCA1 sporadic TRα TRβ TRα TRβ
p negative positive p negative positive p negative positive p negative positive p
Histology
non NST 8 20 ns 4 4 ns 3 5 ns 9 11 ns 15 5 ns
NST 30 66 17 13 15 15 27 39 52 14
Grading
G1, G2 8 38 0.025 2 6 ns 5 3 ns 12 26 ns 28 10 ns
G3 29 48 18 11 12 17 24 24 39 9
pT
pT1 21 25 0.008 12 9 ns 9 12 ns 14 11 ns 18 7 ns
pT2-4 17 61 9 8 9 8 22 39 49 12
pN
pN0 20 28 0.040 13 7 ns 7 13 ns 13 15 ns 19 9 ns
pN1-3 15 51 6 9 10 5 20 31 42 9
pM
pM0 18 23 ns 11 7 ns 7 11 ns 14 9 0.011 16 7 ns
pM1 18 52 8 10 11 7 15 37 41 11
ER
negative 27 27 0.001 14 13 ns 15 12 ns 12 15 ns 21 6 ns
positive 11 44 7 4 3 8 21 23 33 11
PR
negative 27 25 0.001 14 13 ns 14 13 ns 13 12 ns 21 4 ns
positive 11 46 7 4 4 7 20 26 33 13
Her2
negative 22 29 ns 10 12 ns 10 12 ns 14 15 ns 21 8 ns
positive 6 20 4 2 3 3 12 8 17 3
Triple negative
no 17 57 0.002 10 7 ns 7 10 ns 29 28 ns 43 14 ns
yes 12 7 5 7 7 5 3 4 6 1
Patient age
≤ 42 y 22 19 < 0.001 12 10 ns 8 14 ns 6 13 ns 14 5 ns
> 42 y 16 66 9 7 10 6 30 36 52 14