Table 4. TSH, fT3 and fT4 serum levels.

				BRCA1			sporαdic			BRCA1			sporαdic
	BRCA1	sporadic	p	TRα neg.	TRα pos.	p	TRα neg.	TRα pos.	p	TRβ neg.	TRβ pos.	p	TRβ neg.	TRβ pos.	p
TSH
ref. range	10	20		5	5		12	8		4	6		17	3
< ref. range	2	4	ns	1	1	ns	3	1	ns	2	0	ns	2	2	ns
> ref. range	1	2	ns	0	1	ns	1	1	ns	0	1	ns	0	2	0.043
fT3
ref. range	6	10		3	3		6	4		4	2		7	3
< ref. range	0	0	na	0	0	na	0	0	na	0	0	na	0	0	na
> ref. range	0	0	na	0	0	na	0	0	na	0	0	na	0	0	na
fT4
ref. range	7	11		3	4		8	3		4	3		8	3
< ref. range	0	0	na	0	0	na	0	0	na	0	0	na	0	0	na
> ref. range	0	2	ns	0	0	na	1	1	ns	0	0	na	1	1	ns

TSH and thyroid hormone levels in breast cancer patients as quantified at time of first diagnosis are shown. Since clinical data were retrieved retrospectively, data regarding thyroid function were not available in all the cases. ref = reference, ns = not significant, na = not applicable