Table 3.
Adjusted odds ratios of predictors of in-hospital death and sICH
| Variables | In-hospital death
|
sICH
|
||||
|---|---|---|---|---|---|---|
| Adjusted OR | 95% CI | P value | Adjusted OR | 95% CI | P value | |
| Age group | ||||||
| <55 years | Reference | Reference | ||||
| 55–64 years | 1·42 | 0·92–2·18 | 0·11 | 1·19 | 0·60–2·33 | 0·62 |
| 65–74 years | 1·73 | 1·15–2·61 | 0·008 | 2·30 | 1·29–4·08 | 0·005 |
| 75–79 years | 2·01 | 1·29–3·13 | 0·002 | 3·01 | 1·62–5·60 | 0·001 |
| 80+ years | 2·92 | 1·99–4·29 | <0·001 | 3·09 | 1·73–5·51 | 0·0001 |
| Male | 1·24 | 1·02–1·52 | 0·03 | 1·20 | 0·95–1·53 | 0·13 |
| Race-ethnicity | ||||||
| Whites | Reference | Reference | ||||
| Others* | 1·03 | 0·81–1·30 | 0·80 | 0·77 | 0·59–1·01 | 0·06 |
| Time from LKW to IV tPA >3 h | 0·89 | 0·69–1·14 | 0·35 | 0·81 | 0·58–1·14 | 0·23 |
| NIHSS score | 1·11 | 1·10–1·13 | <0·001 | 1·06 | 1·05–1·08 | <0·0001 |
| Medical history | ||||||
| Hypertension | 0·81 | 0·63–1·05 | 0·11 | 1·07 | 0·75–1·52 | 0·70 |
| Dyslipidemia | 0·86 | 0·70–1·05 | 0·14 | 1·34 | 1·05–1·70 | 0·02 |
| MI or CAD | 1·28 | 1·04–1·58 | 0·02 | 0·91 | 0·70–1·18 | 0·46 |
| Heart failure | 1·17 | 0·90–1·51 | 0·25 | 0·90 | 0·64–1·27 | 0·56 |
| Diabetes | 1·14 | 0·92–1·42 | 0·25 | 1·29 | 0·999–1·66 | 0·051 |
| Atrial fibrillation | 1·25 | 1·01–1·57 | 0·046 | 1·19 | 0·91–1·56 | 0·20 |
| Prior stroke | 0·93 | 0·73–1·20 | 0·58 | 0·98 | 0·73–1·32 | 0·90 |
| Smoker | 0·92 | 0·68–1·23 | 0·57 | 0·73 | 0·51–1·06 | 0·10 |
*
Due to the small number of patients who were not white, we collapsed these patients into one group.
sICH, symptomatic intracerebral hemorrhage; OR, odds ratio; CI, confidence interval; LKW, time last known to be well; IV tPA, intravenous tissue plasminogen activator; NIHSS, National Institutes of Health Stroke Scale; MI, myocardial infarction; CAD, coronary artery disease.