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. 2015 Jun 1;212(6):855–864. doi: 10.1084/jem.20141992

Figure 3.

Figure 3.

STAT3-deficient MAIT cells express normal levels of RORγt and PLZF. (A and B) PBMCs from normal controls or STAT3MUT patients were stained with mAbs to identify MAIT cells or total T cells, and then expression of PLZF (A) and RORγt (B) was determined. Representative histogram plots of MAIT or T cells (CD3+Vα7.2-γδ). Graphs show mean ± SEM (n = 6–10) of the MFI normalized to MFI of MAIT cells from controls in each experiment; **, P < 0.01. (C) RORC transcripts were determined by qPCR of sorted T cell populations (n = 5–9). Error bars indicate SEM.