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. 2015 Jun 1;212(6):855–864. doi: 10.1084/jem.20141992

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© 2015 Wilson et al.

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Figure 4. — STAT3-deficient T cells are impaired in their ability to produce IL-17A. (A–D) Unconventional T cell populations (δ2⁻ and δ2⁺ γδ T cells and MAIT cells) and total CD4⁺ and CD8⁺ T cells were isolated from control or STAT3^MUT PBMCs and stimulated with PMA/ionomycin for 72 h. Culture supernatants were then harvested and secretion of IL-17A (A), IFNγ (B), TNF (C), and Granzyme B (D) determined. Graphs show mean ± SEM (n = 5–7); *, P < 0.05.