Table 1.

Left ventricular end-diastolic diameter (LVEDd) normalized to body weight in C57BL/6 and DBKO (M-/Mito-CK −/−) mice, as measured in short-axis MR images. Results are given as mean ± standard deviation in units of mm/g. These results indicate DBKO mice have greater LV dilatation post-hypertrophy vs. C57 mice.

	Control	Hypertrophic
C57	0.15 ± 0.015	0.17 ± 0.019 †
DBKO	0.17 ± 0.017	0.19 ± 0.013 ‡*

^†Significant vs. C57 Control (p=0.0023),

^‡Significant vs. DBKO Control (p=0.0013),

^*Significant vs. C57 Hypertrophic (p=0.0136). Significance is determined by p < 0.05 by Student t- test (C57 Control vs DBKO control, C57 Hypertrophic vs. DBKO Hypertrophic) or paired Student t-test (C57 Control vs. C57 Hypertrophic, DBKO Control vs. DBKO Hypertrophic).