TABLE 4.

Multivariable Analysis of Risk Factors for Ventilator-Associated Conditions and Infection-Related Ventilator-Associated Complications

Variable	OR	95% CI
Ventilator-associated condition multivariable risk factor analysis
Mandatory ventilator modes 100% of days at maximum tidal volume	3.4	1.6–8.0
Net fluid balance (L)	1.2	1.03–1.4
Stress ulcer prophylaxis	1.01	0.998–1.03
Propofol started at intubation	0.48	0.20–1.07
Congestive heart failure	0.40	0.15–0.95
Liver disease	0.12	0.01–0.85
Infection-related ventilator-associated complication multivariable risk factor analysis
Benzodiazepines started between admission and intubation	5.0	1.3–29
Total opioid administered (per 100 μg fentanyl equivalents/kg)	3.3	0.90–16
Paralytic administered while intubated	2.3	0.79–8.0
Minimum tidal volume (mL/kg)	1.5	0.91–2.9
Net fluid balance (L)	1.1	0.90–1.5

OR = odds ratio.

Boldface text highlights comparisons where the 95% confidence interval excludes 1.0.