Table 4.

Inflammatory and Oxidative Stress Biomarkers (n=17)

Biomarkers	Units	Baselinea or Changeb	Soy Nuts	Control Snack	P valuec
CRP	(mg/L)	Baseline	3.4 ± 4.7	3.7 ± 5.5	NS
		Change	1.0 ± 0.4	0.1 ± 0.4
TNF-α	(pg/mL)	Baseline	1.3 ± 0.8	1.3 ± 0.7	NS
		Change	0.01 ± 0.05	−0.03 ± 0.05
IL-6	(pg/mL)	Baseline	2.0 ± 1.0	1.9 ± 1.1	NS
		Change	0.08 ± 0.1	0.2 ± 0.1
IL-18	(pg/mL)	Baseline	49.5 ± 15.2	55.5 ± 18.9	NS
		Change	0.08 ± 0.04	−0.01 ± 0.04
IL-10	(pg/mL)	Baseline	0.2 ± 0.2	0.3 ± 0.1	NS
		Change	1.5 ± 0.8	0.3 ± 0.8
OxLDLd	(U/L)	Baseline	53.0 ± 12.8	48.2 ± 8.4	NS
		Change	−0.1 ± 0.3	0.1 ± 0.3

CRP, C-reactive protein; OxLDL, oxidized LDL; TNF-α, tumor necrosis factor-α.

^aBaseline values are depicted as mean ± SD.

^bRelative change is calculated as (follow-up visit – baseline visit) / baseline visit. These values are depicted as least squares mean (LSM) ± SE.

^cP value corresponds to the transformed variable.

^dn=8