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Dose reduction and delay-related toxicity (out of a total of 86 cycles administered).
| Grade | 3 | 4 |
|---|---|---|
| Gastrointestinal — bloating | 1 | 0 |
| Pain | 2 | 0 |
| Neuro-sensory back/leg pain | 2 | 0 |
| Leg swelling | 1 | 0 |
| LFT elevation | 2 | 0 |
| Thrombocytopenia | 2 | 0 |
| Neutropenia | 0 | 3 |
Abbreviation: LFT = liver function tests.
