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. 2015 Jun 1;10(6):e0127878. doi: 10.1371/journal.pone.0127878

Fig 5. Conversion of astrocytes into neuronal cells which did not pass through the pluripotent stage.

Fig 5

(A) Expressions of Oct4 and Nanog genes as pluripotent markers were not detected following miR-302/367+ valproic acid (VPA) treatment. n = 3. Scale bar: 50 μm. (B) The brain tissue of animals treated with the miR-302/367 cluster were investigated for the teratoma formation. No teratoma formation was observed at 60 days post-injection (dpi). n = 2. Scale bar: 50 μm.