Table 3.

Effect of cardiac muscarinic receptor blockade on HR and HRV

	Pre			Post
	Baseline	Vagal Block*	Δ†	Baseline	Vagal Block*	Δ†
HR, beats/min
Ex	113.4 ± 4.2	187.3 ± 6.2‡	73.9 ± 6.2	105.2 ± 3.9§	174.3 ± 7.3‡	−69.1 ± 3.4
Sed	113.0 ± 10.3	193.6 ± 9.3‡	80.6 ± 10.4	123.9 ± 5.9	192.8 ± 11.8‡	−69.4 ± 12.3
HF, ln ms2
Ex	7.1 ± 0.2	0.1 ± 0.1	−6.9 ± 0.3‡	8.2 ± 0.2§	0.5 ± 0.2‡	−7.6 ± 0.3§
Sed	7.4 ± 0.5	0.4 ± 0.1	−7.1 ± 0.5‡	7.0 ± 0.6	0.3 ± 0.2‡	−6.7 ± 0.5
R-Rsd, ms
Ex	57.8 ± 3.4	7.8 ± 1.0‡	−50.0 ± 3.7	100.5 ± 9.2§	9.9 ± 1.5	−90.6 ± 9.7§
Sed	62.6 ± 11.2	6.7 ± 0.7‡	−56.0 ± 11.3	67.1 ± 7.0	7.9 ± 1.0	−59.2 ± 6.8
R-Rrange, ms
Ex	225.3 ± 13.3	30.7 ± 3.6‡	−194.6 ± 13.7	276.2 ± 12.1§	37.7 ± 5.5	−238.5 ± 13.4§
Sed	226.8 ± 21.7	24.2 ± 2.6‡	−202.6 ± 22.3	194.6 ± 11.8	33.1 ± 5.2	−161.5 ± 14.4§

^*Vagal block, muscarinic receptor blockade (atropine sulfate 50 μg/kg, iv).

^†Change from baseline.

^‡P < 0.01 baseline vs. muscarinic block;

^§P < 0.01 Pre vs. Post.