Blood pressure at the level of the middle cerebral artery (MCA; A), mean cerebral blood flow velocity (B), and cerebrovascular resistance index (C) during supine baseline, 3 different degrees of head-down tilt (HDT), and rapid transitions to 75° head-up tilt (HUT). See Fig. 1 for abbreviations. Significantly different &vs. Control, *vs. −10° HDT condition, #vs. −25° at same period, P < 0.05.