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. 2014 Dec 31;308(11):H1368–H1381. doi: 10.1152/ajpheart.00496.2014

Fig. 6.

Fig. 6.

Experimental EPC/rat cardiac microvascular endothelial cells (RCMVECs) adhesion data. A: raw data from adhesion experiments. Colors represent the treatment conditions for tumor necrosis factor-α (TNF-α) treatment to RCMVECs/EPCs. Black circles, vehicle/vehicle; orange circles, vehicle/TNF-α; blue circles, TNF-α/vehicle; pink circles, TNF-α/TNF-α. B: adhesion data from A integrated with respect to shear stress and averaged (6 runs per group, error bars indicate means ± SD). A two-way ANOVA demonstrated that all four groups were statistically distinct (P < 0.05). *TNF-α treatment to RCMVECs increases adhesion with respect to no treatment. #TNF-α treatment to EPCs increases adhesion with respect to no treatment or TNF-α treatment only to RCMVECs. †TNF-α treatment to EPCs and RCMVECs increases adhesion with respect to no treatment or single TNF-α treatment to RCMVECs or EPCs. C: average bond number expression (relative to 100% high affinity activation, vehicle/vehicle-treated EPC/RCMVEC group) in each experimental group determined by a best-fit mathematical model for low affinity, high affinity, and a 50/50 low/high affinity population.