Fig. 5.

JCR rats were treated with anti-miR-21 or scrambled (scram) anti-miR on day 5 RI or anti-CD11b/CD18 and CD44 blocking antibodies on days 6–9 RI where indicated, and SD or JCR rats underwent 9 days of RI (n = 6). A: arteriolar [smooth muscle-myosin heavy chain (SM-MHC)- and proliferating cell nuclear antigen-positive vessels > 20 μM] and capillary (vessels < 20 μM) densities were determined in cardiac (CZ) cross sections on day 9 RI. B: coronary blood flow was measured in CZ and NZ using microspheres during LAD occlusion and is expressed as the ratio between CZ and NZ flows on day 9 of RI. *P < 0.05 vs. sham; #P < 0.05 vs. WKY RI; §P < 0.05 vs. JCR RI.