Table 4.
Comparison of Pain-Related Outcomes in Alloimmunized vs. Non-alloimmunized SCD Patients
| N* | % of Alloimmunized Patients |
% of Non- alloimmunized Patients |
P value |
|
|---|---|---|---|---|
|
Vaso-occlusive Endpoints
Painful episodes requiring medical attention in past 12 months Painful episodes requiring hospitalization in past 12 months |
294 291 |
77 61 |
71 57 |
0.339 0.539 |
| Hydroxyurea use | 282 | 50 | 48 | 0.708 |
|
Daily home opioid use
Long-acting opioids Short-acting opioids Both long and short-acting opioids |
295 276 275 |
39 47 28 |
24 29 16 |
0.013 0.006 0.030 |
*
Number of subjects for whom data were available.