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. Author manuscript; available in PMC: 2015 Dec 10.
Published in final edited form as: Cell Host Microbe. 2014 Nov 20;16(6):795–805. doi: 10.1016/j.chom.2014.11.002

Figure 6. Effects of selected drugs on virus titers and cell viability in virus-infected cells.

Figure 6

HEK 293 (A) or A549 (B) cells were infected with WSN virus at an MOI of 0.001. One hour later, cells were washed and incubated with medium containing the indicated concentration of golgicide A (A) and ruxolitinib (B). DMSO (final concentration, 1%) was used as a control. Forty-eight hours later, culture supernatants were harvested for virus titration and cell viability was determined by using CellTiter-Glo. Average and standard deviation of 3 replicates are shown. The p value was calculated with Welch’s t-test compared with a non-targeting siRNA control. To control for the multiplicity effect, p values were adjusted using Benjamini-Hochberg’s procedure keeping the false discovery ratio < 0.05. Asterisk indicates that the adjusted p value is < 0.05. See also Figure S6 and Table S6.