Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Repetition of deliberate self-harm
RCT	120 adults aged 18 to 66 years, enrolled within 48 hours of admission to hospital after an episode of deliberate self-harm	Incidence of deliberate self-harm (at least one subsequent suicide attempt) 24% (estimated proportion based on last observation carried forward) with cognitive therapy (10 outpatient sessions) plus usual care 42% (estimated proportion) with usual care Absolute numbers not reported	P = 0.046	Effect size not calculated	cognitive therapy plus usual care
RCT	120 adults aged 18 to 66 years, enrolled within 48 hours of admission to hospital after an episode of deliberate self-harm	Episodes of deliberate self-harm (re-attempt rate per person) with cognitive therapy (10 outpatient sessions) plus usual care with usual care Absolute results not reported	HR 0.51 95% CI 0.26 to 0.997 P = 0.045	Small effect size	cognitive therapy plus usual care
RCT	120 adults aged 18 to 66 years, enrolled within 48 hours of admission to hospital after an episode of deliberate self-harm	Episodes of deliberate self-harm (re-attempt rate per person) with cognitive therapy (10 outpatient sessions) plus usual care with usual care Absolute results not reported	Controlled for baseline depression scores: HR 0.47 95% CI 0.24 to 0.93 P = 0.03	Moderate effect size	cognitive therapy plus usual care
RCT	120 adults aged 18 to 66 years, enrolled within 48 hours of admission to hospital after an episode of deliberate self-harm	Episodes of deliberate self-harm (re-attempt rate per person) with cognitive therapy (10 outpatient sessions) plus usual care with usual care Absolute results not reported	Controlled for age, sex, and minority status HR 0.52 95% CI 0.26 to 1.02 P = 0.06		Not significant
RCT	77 people aged 15 to 35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Mean episodes of deliberate self-harm per person 0–3 months 5.63 with cognitive behavioural therapy (12 outpatient sessions) plus usual care 5.65 with usual care	Reported as not significant		Not significant
RCT	77 people aged 15 to 35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Mean episodes of deliberate self-harm per person 3–6 months 5.30 with cognitive behavioural therapy (12 outpatient sessions) plus usual care 4.03 with usual care	Reported as not significant		Not significant
RCT	77 people aged 15 to 35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Mean episodes of deliberate self-harm per person 6–9 months 1.18 with cognitive behavioural therapy (12 outpatient sessions) plus usual care 4.58 with usual care	P <0.05	Effect size not calculated	cognitive behavioural therapy plus usual care
Suicide
RCT	77 people aged 15 to 35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Suicide 0–3 months 0/40 (0%) with cognitive behavioural therapy (12 outpatient sessions) plus usual care 0/33 (0%) with usual care	Reported as not significant		Not significant
RCT	77 people aged 15 to 35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Suicide 3–6 months 0/40 (0%) with cognitive behavioural therapy (12 outpatient sessions) plus usual care 1/33 (3%) with usual care	Reported as not significant		Not significant
RCT	77 people aged 15 to 35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Suicide 6–9 months 0/40 (0%) with cognitive behavioural therapy (12 outpatient sessions) plus usual care 1/33 (3%) with usual care	Reported as not significant		Not significant
Admission to hospital
RCT	77 people aged 15–35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Psychiatric hospitalisations 0–3 months 2/40 (5%) with cognitive behavioural therapy (12 outpatient sessions) plus usual care 14/33 (42%) with usual care	Reported as not significant		Not significant
RCT	77 people aged 15–35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Psychiatric hospitalisations 3–6 months 6/40 (15%) with cognitive behavioural therapy (12 outpatient sessions) plus usual care 16/33 (48%) with usual care	Reported as not significant		Not significant
RCT	77 people aged 15–35 years with recent (within 1 week) deliberate self-poisoning or self-injury	Psychiatric hospitalisations 6–9 months 2/40 (5%) with cognitive behavioural therapy (12 outpatient sessions) plus usual care 21/33 (64%) with usual care	P <0.05	Effect size not calculated	cognitive behavioural therapy plus usual care