Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Repetition of deliberate self-harm
Systematic review	People aged >15 years 5 RCTs in this analysis	Repetition of deliberate self-harm 6–12 months 45/290 (16%) with problem-solving therapy 54/281 (19%) with usual care	Peto OR 0.71 95% CI 0.45 to 1.11 P = 0.13		Not significant
RCT	1094 people aged >16 years enrolled within 38 hours of presenting to hospital with self-harm	Repetition of deliberate self-harm 12 months 70/522 (13%) with problem-solving therapy plus usual care 81/572 (14%) with usual care	RRR +0.05 95% CI –0.28 to +0.30 P = 0.79		Not significant
RCT	1094 people aged >16 years enrolled within 38 hours of presenting to hospital with self-harm	Repetition of deliberate self-harm 12 months 28/208 (14%) with problem-solving therapy plus usual care 47/212 (22%) with usual care	RRR 0.39 95% CI 0.07 to 0.60 P = 0.03	Effect size not calculated	problem-solving therapy
RCT	1094 people aged >16 years enrolled within 38 hours of presenting to hospital with self-harm	Repetition of deliberate self-harm 12 months 42/314 (13%) with problem-solving therapy plus usual care 34/360 (9%) with usual care	RRR –0.42 95% CI –1.17 to +0.08 P = 0.37		Not significant