Table 5. Prognostic factors for disease free interval of the 169 EEC patients.

Variables	Univariate analysis HR (95% CI)*	p value	Multivariate analysis HR (95% CI)*	p value
Age at diagnosis (years, continuous)	1.04 (0.98-1.10)	0.18
FIGO stage (III & IV vs. I & II)	3.14 (1.60-7.14)	0.01	2.68 (0.33-22.1)	0.359
Tumor grade (3 vs. 1&2)	2.65 (0.59-11.9)	0.20
Myometrial invasion (>1/2 vs. < 1/2)	1.42 (0.48-4.25)	0.53
Lymph node metastases (yes vs. no)	4.51 (1.21-16.83)	0.025	2.33 (0.39-14.0)	0.356
uPA expression level (high vs. low)+	3.38 (1.20-9.49)	0.021	4.65 (1.16-11.5)	0.030

^*Cox regression model.

⁺high expressed: uPA/GADPH>0.015, low expressed: uPA/GADPH<0.015.