Table II.
Hemodynamics and laboratory test results on admission across RAP/PCWP ratio quartiles (n = 367)
| Q1 (<0.43) | Q2 (0.43-0.58) | Q3 (0.58-0.75) | Q4 (≥0.75) | P | |
|---|---|---|---|---|---|
| MAP (mm Hg) | 85 (76-92) | 80 (73-90) | 81 (75-90) | 78 (69-90) | .053 |
| RAP (mm Hg) | 10 (8-12) | 15 (12-18) | 18 (15-21) | 22 (18-26) | <.0001 |
| Pulmonary systolic pressure (mm Hg) | 61 (52-72) | 60 (52-68) | 58 (49-70) | 49 (40-65) | <.0001 |
| Pulmonary diastolic pressure (mm Hg) | 30 (28-37) | 30 (27-35) | 30 (25-35) | 27 (22-33) | .0003 |
| Mean pulmonary pressure (mm Hg) | 42 (37-47) | 41 (35-46) | 41 (34-47) | 34 (28-43) | <.0001 |
| Pulmonary capillary wedge pressure (mm Hg) | 30 (26-33) | 29 (24-33) | 26 (23-31) | 23 (18-28) | <.0001 |
| Cardiac index (L/min/m2) | 1.7 ± 0.4 | 1.7 ± 0.5 | 1.8 ± 0.7 | 1.9 ± 0.7 | .03 |
| PCWP - RAP (mm Hg) | 20 (17-22) | 14 (11-16) | 9 (7-10) | 1 (-2to4) | <.0001 |
| Systemic vascular resistance (dyn · s/cm5) | 1673 (1414-2069) | 1571 (1264-1898) | 1382 (1115-1863) | 1278 (951-1640) | <.0001 |
| Pulmonary vascular resistance (Wood units) | 2.8 (1.9-5.0) | 3.3 (2.1-4.6) | 3.5 (2.2-5.5) | 3.3 (1.9-5.5) | .67 |
| Stroke volume (mL) | 42 (34-54) | 42 (34-54) | 44 (33-56) | 41 (31-55) | .99 |
| Right ventricular stroke work index (g · m/m2 per beat) | 9.2 (7.0-11.6) | 6.9 (5.8-8.8) | 6.7 (4.4-8.9) | 3.5 (2.7-7.3) | <.0001 |
| Brain natriuretic peptide (pg/mL) | 737 (344-1374) | 1237 (745-2568) | 889 (550-1473) | 972 (469-1797) | .06 |
| Sodium (mEq/L) | 137 ± 4 | 135 ± 6 | 136 ± 5 | 134 ± 14 | .09 |
| Creatinine (mg/dL) | 1.2 (1.0-1.7) | 1.3 (1.0-1.8) | 1.5 (1.1-1.9) | 1.6 (1.1-2.5) | .0004 |
| Blood urea nitrogen (g/dL) | 29 (22-39) | 33 (22-55) | 38 (22-66) | 45 (27-70) | .009 |
| Bilirubin (mg/dL) | 1.0 (0.5-1.4) | 1.2 (0.6-1.8) | 1.1 (0.6-1.3) | 1.2 (0.7-1.7) | .42 |
| ALT (IU/L) | 26 (19-44) | 38 (18-75) | 27 (16-45) | 22 (14-37) | .41 |
| AST (IU/L) | 24 (19-38) | 36 (25-51) | 30 (19-46) | 26 (19-46) | .23 |
P values for continuous variables calculated via ANOVA or Kruskal-Wallis test. Values are expressed as mean ± SD or median (IQR). Missing values: brain natriuretic peptide, 158; blood urea nitrogen, 105; bilirubin, 169; aspartate aminotransferase, 167; alanine aminotransferase, 167. Abbreviations: ALT, Alanine aminotransferase; AST, aspartate aminotransferase.