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. 2015 Jun 2;6:520. doi: 10.3389/fmicb.2015.00520

TABLE 2.

Effects of the inhibitors on the host protozoa cell cycle and symbiont division.

Cycloheximide m-divi1 Aphidicolin Camptothecin Oryzalin
A. deanei G1/S-phase arrest
Inhibition of symbiont cytokinesis Did not affect cell cycle progression or symbiont division Maximum of 4 symbiont nucleoids per cell G2/M-phase arrest Symbiont filamentation
S. culicis G1/S-phase arrest Symbiont filamentation G2/M-phase arrest Inhibition of symbiont cytokinesis