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. 2015 Jun 2;6:533. doi: 10.3389/fmicb.2015.00533

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Copyright © 2015 Li, Tang, Suo, Qin, Yin, Liu and Suo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IgY (IgG) antibody titer in the serum and oocyst output post primary and boost immunization. (A) The OD₄₅₀ value was similar between the birds immunized with EmiChIL-2 and those, immunized with the wild-type E. mitis 2 weeks after both the primary and the boost immunization (p > 0.05). (B) Mean total oocyst output per chicken of EmiChIL-2 was significantly lower than that of the wild-type E. mitis after the primary immunization (p < 0.05) 4–8 days, whereas, there was no significant difference between the EmiChIL-2 and the wild-type E. mitis-immunized birds after the boost immunization (p > 0.05) 4 to 8 days.