Patients with hypertrophic cardiomyopathy and SDB. A, Decreased pkVO2. B, Decreased calculated functional capacity in METs. C and D, Decreased percentage of predicted pkVO2. *Adjusted for age, sex, BMI, β-blocker use, calcium channel antagonist use, rhythm during exercise testing, and history of coronary artery disease, COPD, and diabetes mellitus. MET = metabolic equivalent; pkVO2 = peak oxygen consumption; SDB = sleep-disordered breathing; VO2 = oxygen consumption.