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. 2015 May 22;21:1469–1477. doi: 10.12659/MSM.893291

Table 2.

Renal parameters in rats after galactosamine injection.

Gr. (n) Creats mg/dl Ureas mg/dl Creat cl ml/min Nas mmol/l Ks mmol/l Osmolp mosmol/kg Creatu mg/dl Ureau mg/dl Nau mmol/l Ku mmol/l Nau 24 h mmol/24 h FENa% Osmolu mosmol/kg Osmol cl ml/24 h FW cl ml/24 h Osmu/osmp Creatu/creats FW reab ml/24 h SGu Proteinu (mg/dl) Proteinu 24 h mg/24 h 24 h urine ml/24 h
1 (12) sham 0.47 ±0.04 33.7 ±3.8 0.89 ±0.4 142.6 ±1.4 5.82 ±0.46 308.1 ±3.5 50.4 ±14.3 3244 ±973.9 52 ±15.79 191. ±39.2 0.61 ±0.23 0.4 ±0.018 1480.7 ±69.3 57.3 ±13.9 -45.3 ±10.9 4.8 ±0.21 108.2 ±38 45.3 ±10.9 1.001 ±0.003 193.25 ±72.63 22.86 ±10.86 11.9 ±2.9
2 (12) GAL 0.76 ±0.09 80.1 ±10.1 0.18 ±0.12 142.3 ±1.1 5.90 ±0.47 323.2 ±3.9 37.9 ±22.4 2484.6 ±1787.1 46.25 ±12.73 70.8 ±27.2 0.24 ±0.15 0.17 ±0.12 1528.6 ±95.5 24.09 ±10.7 -19.04 ±8.6 4.7 ±0.31 49.5 ±27.7 19.04 ±8.6 1.005 ±0.006 143.75 ±72.61 8.12 ±5.91 5.05 ±2.1
gr 2 v gr 1 − p p<0.001* p<0.001* p<0.0012* p<0.71 p<0.76 p<0.003* p<0.23 p<0.34 p<0.46 p<0.001* p<0.003 p<0.016* p<0.30 p<0.001* p<0.001* p<0.27 p<0.0052* p<0.001* p<0.17 p<0.22 p<0.007 p<0.003*
*

p<0.05.

24 h urine – twenty-four-hour urine collection; creats – serum creatinine; ureas – serum urea; creat cl – creatinine clearance; Nas – serum sodium; Ks – serum potassium; osmolp – plasma osmolality; creatu – urine creatinine; ureau – urine urea; Nau – urine sodium; Ku – urine potassium; Nau 24 h – 24 h urine sodium excretion; osmolu – urine osmolality; osmol cl – osmolal clearance; FW cl – free water clearance; FENa% – ejected fraction of sodium; osmu/osmp – urine osmolality/plasma osmolality ratio; creatu/creats – urine creatinine/serum creatinine ratio; FW reab – free water reabsorption; SGu – specific gravity of urine; proteinu – concentration of protein in urine; proteinu 24 h – 24h proteinuria, p – value of p. Biochemical parameters were evaluated 48 hours after saline or gal injection. 24h urine samples were collected during 24 hours from 24th to 48th hour after saline or gal injection and evaluated 48 hours after saline or gal injection. Values are means ±SE, significance – p<0.05. Group 1 – sham, group 2 – given 1.1 g/kg of GAL.