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. 2015 Jun 2;5:10729. doi: 10.1038/srep10729

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Copyright © 2015, Macmillan Publishers Limited

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(A) Activation of microglia with MPP⁺ increased Lf release, which was further enhanced by initial FAC incubation. (B) Lf mRNA levels in MPP⁺ activated microglia was increased compared with control group. Iron load in microglia elevated the Lf mRNA expression compared with MPP⁺ group. Data are presented as fold changes in Lf mRNA expression with treatment vs control in microglia. *P < 0.05, compared with the control; ^#P < 0.05, compared with MPP⁺ group. n = 6.