Table 3.
Predictors of agitationa
| Variable: | Odds ratios | 95% CI | LR p-value |
|---|---|---|---|
| On admission to the ICU | |||
| Past medical history of illicit substance use | 2.43 | 1.18 – 5.15 | 0.015 |
| Height | 1.04 | 1.01 – 1.08 | 0.016 |
| SOFA respiratory subscore | 1.58 | 1.11 – 2.28 | 0.0097 |
| SOFA CNS subscore | 1.90 | 1.45 – 2.54 | <.0001 |
| Use of restraints | 3.77 | 1.39 – 11.53 | 0.008 |
| 24 hrs prior to onset of first agitation event | |||
| Past medical history of psychiatric diagnosis | 6.24 | 1.4 – 32.4 | 0.015 |
| Height | 1.06 | 1.01 – 1.12 | 0.015 |
| SOFA score | 2.3 | 2.1 – 2.6 | 0.012 |
| P/F <200 mmHg | 4.7 | 1.4 – 17.9 | 0.011 |
| Serum pH | 1.3b | 1.02b – 1.75b | 0.026 |
| Restraints (1% of time) | 1.04 | 1.01 – 1.08 | 0.0003 |
| Mechanical ventilation (1% of time) | 1.03 | 1.01 – 1.04 | 0.0004 |
| Pain | 1.2 | 1.05 – 1.4 | 0.0059 |
| Presence of GU catheter | 3.8 | 1.2 – 12.98 | 0.0264 |
a
At least one observation of agitation during the study time
Abbr: Sequential Organ Failure Assessment (SOFA); central nervous system (CNS); PaO2/FiO2 (P/F); Likelihood Ratio (LR)
b
for each 0.05 increase in pH